Determinants of Unresponsiveness to Treatment in Cutaneous Leishmaniasis: A Focus on Anthroponotic Form Due to Leishmania tropica
نویسندگان
چکیده
منابع مشابه
Unresponsiveness to Glucantime Treatment in Iranian Cutaneous Leishmaniasis due to Drug-Resistant Leishmania tropica Parasites
BACKGROUND Recent circumstantial evidence suggests that an increasing number of Iranian patients with cutaneous leishmaniasis are unresponsive to meglumine antimoniate (Glucantime), the first line of treatment in Iran. This study was designed to determine whether the clinical responses (healing, or non-healing) were correlated with the susceptibility of Leishmania parasites to Glucantime. MET...
متن کاملInterferon Gamma Unresponsiveness Due to Down-Regulation of IFN-γR Expression in Experimental Cutaneous Leishmaniasis
It is now well documented that interferon gamma (IFN-γ) is the indispensable cytokine for inducing protective immunity against experimental and human cutaneous leishmaniaisis. The importance of IFN-γ receptor (IFN-γR) has also been studied. In the present study, we made attempts to find out whether L. major infection is able to alter the expression of IFN-γR in vivo. In addition, we studied the...
متن کاملemergence of cutaneous leishmaniasis due to leishmania major in a new focus of southern iran
reports from the health center of kerman province, southern iran showed an increasing of cutaneous leishmaniasis cases in orzuieh rural district, southwest of the province in 2003. the report encouraged the team to carry out an epidemi ological survey in the district during 2003-2004. the objectives were to determine the ecology of sand flies, potential reser voir hosts and human infection. a t...
متن کاملA New Focus of Anthroponotic Cutaneous Leishmaniasis in Dehbakry Region of Bam District, Southeastern Iran 2008
Background and aims: Cutaneous leishmaniasis (CL) is still a health problem in the world, including Iran where its cases have significantly increased in recent years. The objective of this study was to assess a new focus of anthroponotic CL in rural communities after the earthquake in Bam district. Method: After the report of the provincial health authorities, this study has been carried out...
متن کاملEmergence of Cutaneous Leishmaniasis due to Leishmania major in a New Focus of Southern Iran
Reports from the health center of Kerman Province, southern Iran showed an increasing of cutaneous leishmaniasis cases in Orzuieh Rural District, southwest of the province in 2003. The report encouraged the team to carry out an epidemiological survey in the district during 2003-2004. The objectives were to determine the ecology of sand flies, potential reservoir hosts and human infection. A tot...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2021
ISSN: 1664-302X
DOI: 10.3389/fmicb.2021.638957